Cells bulge to squeeze through barriers

Cells bulge to squeeze through barriers. Nov. 27, 2017. Duke scientists have discovered a new tool in the cell’s invasion machinery that may help explain cancer’s ability to spread. Time-lapse imaging of the worm C. elegans reveals a fleeting protrusion that wedges into a tiny gap in the protective layer that surrounds the cell, and swells until the breach is wide enough for the cell to squeeze through. The findings could point to new ways to prevent metastasis, the leading cause of cancer-related deaths. Picked up by Futurity and STAT.